Contents

• The Residual Nephron Hypothesis

• Progression of Functional Impairment

• Stages of Dysfunction

• Syndromes
  
• Nephrotic
  
• Nephritic
  
• Tubulointerstitial
  
• Chronic Renal Failure
  
• Acute Renal Failure
• Progressive Impairment of Individual Functions
1. Glomerular Filtration Rate
2. Regulation of Fluid Balance
• Concentrating Ability
• Diluting Ability
3. Excretion of Acid, Phosphate, Urate
4. Deficient Elaboration of active Vitamin D and secondary HyperParathyroidism
5. Deficient Elaboration of Erythropoietin and Anemia
6. Sodium and Potassium Balance